It is also thought to have antibacterial and anti-inflammatory effects.
It has been used for centuries in traditional medicine to treat a variety of conditions such as diabetes and high cholesterol. It is known for its bitter taste and yellow color. Interaction Ratingīerberine is a naturally-occurring compound that is found in several plants, including goldenseal, barberry, goldthread, phellodendron, and Oregon grape. Theoretically, use of berberine with drugs metabolized by CYP2D6 might increase drug levels and increase the risk of adverse effects. In vitro research and preliminary clinical evidence show that berberine can inhibit CYP2D6. Theoretically, berberine might increase serum levels of drugs metabolized by CYP2D6. Metoprolol is classified as belonging to the following Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension. A biochemical study on the hypotensive effect of berberine in rats.
Study of some pharmacological actions of berberine. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists Moderate Likelihood of Occurrence Possible
